Precipitation of proteins by vinblastine and calcium ions.
Proceedings of the National Academy of Sciences of the United States of America, 66(3): 807-14 PMID 5269244 DOI 10.1073/pnas.66.3.807
Abstract
We have found that vinblastine sulfate can precipitate a number of proteins in addition to microtubule protein. Those proteins which precipitate with vinblastine sulfate, all of which were derived from structure, also precipitate with Ca(2+) ions. Our results suggest that vinblastine sulfate, presumably acting as a cation, precipitates proteins by combining with sites which can also combine with Ca(2+) ions.