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MicroPubl Biol · 2025

Ce -NeRV3D - a C. elegans Neuron RNA-seq Visualization tool in 3D.

microPublication biology, 2025 PMID 41210177 DOI 10.17912/micropub.biology.001830

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Abstract

Caenorhabditis elegans provides a tractable model for neural circuit studies, with complete connectomes and single-cell transcriptomic atlases available. Here, we present Ce -NeRV3D ( C. elegans Neuron RNA-seq Visualization tool in 3D), a Blender plug-in that allows visualizing the expression patterns of an unlimited number of genes within the worm's 3D nervous system. The tool enables users to explore the spatial distribution of gene co-expression with customizable color mapping, overlay single-cell RNA sequencing data onto the anatomical structure, and interactively examine transcriptomic datasets in the context of detailed neural anatomy.

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