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Methods Mol Biol · 2025

The Application of Base-Editing Technology to Investigate Virus-Host Interactions and Antiviral Therapeutic Strategies.

Methods in molecular biology (Clifton, N.J.), 2940: 251-260 PMID 40515917 DOI 10.1007/978-1-0716-4615-1_22

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Abstract

Understanding viral pathogenesis and developing effective countermeasures hinge on deciphering the complex relationships between viruses and their hosts. While conventional approaches have shown limitations in unraveling these intricate interactions, researchers are now turning to cutting-edge genetic tools, particularly base-editing technology. This section explores how base editing can be innovatively applied to investigate virus-host dynamics and to create novel antiviral therapeutic approaches.

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