Research progress in gene editing technology.
Frontiers in bioscience (Landmark edition), 26(10): 916-927 PMID 34719215 DOI 10.52586/4997
Abstract
As a tool for modifying the genome, gene editing technology has developed rapidly in recent years, especially in the past two years. With the emergence of new gene editing technologies, such as transposon editing tools, numerous advancements have been made including precise editing of the genome, double base editing, and pilot editing. This report focuses on the development of gene editing tools in recent years, elaborates the progress made in classic editing tools, base editor and other new editing tools, and provides insights into challenges and opportunities.