Mapping human brain organoids on a spatial atlas.
Cell stem cell, 28(6): 983-984 PMID 34087156 DOI 10.1016/j.stem.2021.05.004
Abstract
Brain organoids are tridimensional, self-organizing cultures derived from pluripotent stem cells that recapitulate aspects of human neurodevelopment and can be applied toward investigating neural disease and evolution. In this issue of Cell Stem Cell, Fleck et al. (2021) describe a computational platform for mapping cell identity in organoids.