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Prog Mol Biol Transl Sci · 2021

CRISPR-based pathogenic fungal genome editing for control of infection and disease.

Progress in molecular biology and translational science, 179: 161-196 PMID 33785176 DOI 10.1016/bs.pmbts.2020.12.016

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Abstract

Fungi play important roles in many aspects of human life, such as in various food, beverage, agricultural, chemical, and pharmaceutical industries. Meanwhile, some fungal species cause several severe diseases in plants, humans and animals. Fungal and fungal-like diseases pose a severe threat to human health, food security, and ecosystem health worldwide. This chapter introduces CRISPR-based genome editing technologies for pathogenic fungi and their application in controlling fungal diseases.

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