Pac-Man like DNA cut-and-paste tool allows larger gene edits.
Communications biology, 3(1): 709 PMID 33219320 DOI 10.1038/s42003-020-01446-7
Аннотация
The CRISPR-Cas toolbox allows genetic manipulation of cultured cells, plants and animals on the basis of simpler RNA-guided DNA recognition. It has provided breakthrough scientific opportunities to engineer desirable traits, cure genetic diseases and enable point-of-care diagnostics. A recent study by Joseph Bondy-Denomy and colleagues further equips this toolbox to cut larger chunks of DNA from a cell’s genome.