Prime Editing: Game Changer for Modifying Plant Genomes.
Trends in plant science, 25(8): 722-724 PMID 32513585 DOI 10.1016/j.tplants.2020.05.008
Abstract
Prime editing, developed by Anzalone et al., brings genome editing to a new level, because this approach allows introduction of all mutation types, including insertions, deletions, and all putative 12 types of base-to-base conversions. Previously tested in human cells, this technique has been adapted for use in plants by Lin et al.