An Exclusive Interview With CRISPR.
AMA journal of ethics, 21(12): E1079-1088 PMID 31876473 DOI 10.1001/amajethics.2019.1079
Аннотация
This article chronicles a didactic encounter between an ethics-minded physician-scientist and a personified genome editing technology called clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins, commonly abbreviated as CRISPR/Cas, or simply CRISPR. The interview considers clinically and ethically relevant questions about this technology related to patient safety, therapeutic efficacy, equitable access, and global governance of humanity's genetic legacy.