Black Swans of CRISPR: Stochasticity and Complexity of Genetic Regulation.
BioEssays : news and reviews in molecular, cellular and developmental biology, 41(7): e1900032 PMID 31090950 DOI 10.1002/bies.201900032
Abstract
Recent waves of controversies surrounding genetic engineering have spilled into popular science in Twitter battles between reputable scientists and their followers. Here, a cautionary perspective on the possible blind spots and risks of CRISPR and related biotechnologies is presented, focusing in particular on the stochastic nature of cellular control processes.