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Adv Gerontol · 2018

[The prospects of using the technology of genome editing for correction of neurodegenerative diseases.].

Advances in gerontology = Uspekhi gerontologii, 31(6): 892-903 PMID 30877819

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Abstract

We reviewed the results of modern studies using gene therapy methods for correction of neurodegenerative diseases. We analyzed approaches based on the technologies of gene editing and their prospective use in medicine. We discussed some limitations associated with the features of pathogenesis of neurodegenerative diseases for application of the genome editing tools directing to for the treatment of these pathologies.

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