CRISPR-Cas Systems Reduced to a Minimum.
Molecular cell, 73(4): 641-642 PMID 30794791 DOI 10.1016/j.molcel.2019.02.005
Аннотация
In two recent studies in Molecular Cell, Wright et al. (2019) report complete spacer integration by a Cas1 mini-integrase and Edraki et al. (2019) describe accurate genome editing by a small Cas9 ortholog with less stringent PAM requirements.