Physiological Models of Human Neuronal Development and Disease.
Neuron, 100(5): 1025-1027 PMID 30521777 DOI 10.1016/j.neuron.2018.11.026
Abstract
Human neural network development occurs at stages inaccessible to longitudinal monitoring. By transplanting human neurons to the adult mouse brain, recent studies explore human neural circuit formation in realistic cellular and physiological environments, establishing new models for human neurodevelopmental disorders.